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William L Young Selected Research

Arteriovenous Malformations (Arteriovenous Malformation)

4/2015Current surgical results with low-grade brain arteriovenous malformations.
3/2014De novo cerebrovascular malformation in the adult mouse after endothelial Alk1 deletion and angiogenic stimulation.
2/2014Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial.
1/2014Distinctive distribution of lymphocytes in unruptured and previously untreated brain arteriovenous malformation.
2/2013Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain.
12/2012G Protein-Coupled Receptor 124 (GPR124) Gene Polymorphisms and Risk of Brain Arteriovenous Malformation.
8/2012Brain-derived neurotrophic factor Val66Met polymorphism predicts worse functional outcome after surgery in patients with unruptured brain arteriovenous malformation.
7/2012Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue.
7/2012Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation.
7/2012Bevacizumab attenuates VEGF-induced angiogenesis and vascular malformations in the adult mouse brain.
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William L Young Research Topics

Disease

33Arteriovenous Malformations (Arteriovenous Malformation)
04/2015 - 04/2003
20Hemorrhage
12/2016 - 10/2004
11Rupture
07/2013 - 10/2005
10Stroke (Strokes)
07/2014 - 01/2002
8Hereditary Hemorrhagic Telangiectasia
01/2014 - 02/2004
8Intracranial Aneurysm (Cerebral Aneurysm)
07/2013 - 02/2002
7Aneurysm (Aneurysms)
07/2013 - 10/2005
7Infarction (Infarctions)
10/2011 - 10/2006
7Brain Ischemia (Cerebral Ischemia)
09/2009 - 02/2002
6Ischemic Stroke
01/2016 - 01/2004
6Inflammation (Inflammations)
07/2013 - 06/2006
6Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
08/2011 - 09/2002
6Vascular Remodeling
09/2009 - 03/2007
5Intracranial Hemorrhages (Intracranial Hemorrhage)
09/2012 - 03/2005
5Vascular Diseases (Vascular Disease)
06/2012 - 08/2004
5Cerebrovascular Disorders (Cerebrovascular Occlusion)
11/2011 - 01/2002
5Ischemia
10/2011 - 10/2006
4Brain Injuries (Brain Injury)
07/2014 - 10/2006
4Hypertension (High Blood Pressure)
01/2011 - 01/2002
3Vascular Malformations
04/2013 - 02/2004
3Hypoxia (Hypoxemia)
08/2009 - 09/2006
2Central Nervous System Vascular Malformations (Dural Arteriovenous Fistula)
04/2013 - 01/2008
2Disease Progression
04/2013 - 06/2008
2Wounds and Injuries (Trauma)
03/2013 - 05/2004
2Epilepsy (Aura)
07/2012 - 03/2007
2Atrophy
12/2011 - 04/2010
2Neoplasms (Cancer)
11/2010 - 01/2003
2Cerebral Infarction
09/2009 - 04/2008
2Intracranial Vasospasm
11/2004 - 09/2002
1Hemorrhagic Stroke
01/2014
1Bone Fractures (Bone Fracture)
06/2013
1Postoperative Cognitive Complications
03/2013
1Tibial Fractures (Fracture, Tibial)
03/2013
1Pulmonary Edema
12/2012
1Ruptured Aneurysm
12/2012
1Shock
07/2012
1Seizures (Absence Seizure)
07/2012
1Respiratory Insufficiency (Respiratory Failure)
07/2012
1Central Nervous System Diseases (CNS Diseases)
07/2012

Drug/Important Bio-Agent (IBA)

13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2013 - 02/2004
9CytokinesIBA
06/2013 - 10/2004
7EndoglinIBA
07/2014 - 02/2004
7Activin Receptors (Activin Receptor)IBA
03/2014 - 02/2004
7Matrix Metalloproteinases (MMPs)IBA
09/2009 - 04/2003
5Biomarkers (Surrogate Marker)IBA
07/2013 - 03/2009
5Ferrosoferric Oxide (Magnetite)FDA Link
07/2013 - 04/2012
5Interleukin-6 (Interleukin 6)IBA
03/2009 - 01/2006
4Doxycycline (Periostat)FDA LinkGeneric
07/2012 - 01/2005
4Proteins (Proteins, Gene)FDA Link
09/2011 - 01/2006
4Matrix Metalloproteinase 9 (Gelatinase B)IBA
06/2008 - 01/2005
3cresyl violetIBA
12/2012 - 10/2006
3Minocycline (Cyclops)FDA LinkGeneric
07/2012 - 09/2007
3Tetracycline (Achromycin)FDA LinkGeneric
07/2012 - 08/2004
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2009 - 01/2006
3Phenobarbital (Luminal)FDA Link
03/2009 - 10/2003
3Verapamil (Calan)FDA LinkGeneric
02/2003 - 01/2002
2ferric ferrocyanide (Prussian blue)FDA Link
12/2016 - 04/2012
2Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2016 - 01/2014
2IronIBA
01/2014 - 04/2012
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
07/2013 - 02/2013
2Clodronic Acid (Clodronate)IBA
03/2013 - 03/2009
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2013 - 12/2012
2Dinoprostone (PGE2)FDA Link
02/2013 - 12/2012
2Transforming Growth Factor beta (TGF-beta)IBA
01/2013 - 10/2005
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
12/2012 - 11/2010
2Anti-Bacterial Agents (Antibiotics)IBA
07/2012 - 08/2004
2Brain Natriuretic Peptide (Natrecor)FDA Link
08/2011 - 07/2005
2Phosphotransferases (Kinase)IBA
09/2010 - 10/2005
2Activins (Activin)IBA
09/2010 - 10/2005
2Anesthetics (Anesthetic Agents)IBA
03/2010 - 02/2002
2Insulin-Like Growth Factor I (IGF-1)IBA
09/2009 - 04/2008
2Matrix Metalloproteinase InhibitorsIBA
09/2009 - 09/2007
2Apolipoproteins E (ApoE)IBA
03/2009 - 10/2007
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
04/2008 - 06/2004
2TetracyclinesIBA
01/2008 - 10/2005
2ApolipoproteinsIBA
10/2007 - 05/2006
2PapaverineIBA
11/2004 - 04/2002
2Complementary DNA (cDNA)IBA
02/2004 - 01/2003
2Phenylephrine (Neo-Synephrine)FDA LinkGeneric
02/2003 - 01/2002
2Adenosine (Adenocard)FDA LinkGeneric
04/2002 - 02/2002
2Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric
02/2002 - 01/2002
1IntegrinsIBA
12/2016
1Indicators and Reagents (Reagents)IBA
01/2014
1Neutralizing AntibodiesIBA
06/2013
1HMGB1 Protein (HMG1)IBA
06/2013
1AlarminsIBA
06/2013
1Monoclonal AntibodiesIBA
02/2013
1Cyclooxygenase 1IBA
02/2013
1EnzymesIBA
12/2012
1Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2012
1perlecanIBA
07/2012
1Anticonvulsants (Antiepileptic Drugs)IBA
07/2012
1Pentylenetetrazole (Metrazol)IBA
07/2012

Therapy/Procedure

17Therapeutics
04/2015 - 09/2002
6Anesthesia
09/2011 - 09/2002
3Aftercare (After-Treatment)
07/2014 - 11/2004
2Endovascular Procedures
06/2012 - 09/2007
1Intraperitoneal Injections
06/2013
1General Anesthesia
03/2013
1Catheters
09/2012